Ernest Cutz is Professor Emeritus of the Department of Laboratory Medicine and Pathobiology at the University of Toronto, and a former senior pathologist in the Department of Paediatric Laboratory Medicine and Senior Research Associate at the Hospital for Sick Children's Research Institute.
This year’s Nobel prize for Physiology and Medicine, awarded to Drs. William Kaelin, Gregg Semenza and Sir Peter Ratcliffe for discovering details of how the body’s cells sense and react to low oxygen levels, is a remarkable feat for several reasons. The Nobel Committee cited the discoveries as ”one of life’s most essential adaptive processes”. The laureates' research answers profound questions about how the body works, helping to inform potential new therapeutic targets to treat cancer and other diseases. While I rejoiced in this remarkable accomplishment by these exceptional clinician-scientists, I was reminded of a colossal failure of the grant review process for medical research funding in Canada. ...continue reading