Podcast author interviews: seasonal variability of leg cramps + safety concerns of quinine

CMAJ is now offering author interviews as part of our regular podcasts. This week:

Audio interview with Dr. David Hogan, geriatric medicine specialist at the University of Calgary. Quinine sulfate is widely used off label to treat nocturnal leg cramps in Canada. Although modestly effective for this indication, the drug has many potential moderate and severe adverse effects.

Interview with Dr. Scott Garrison, associate professor in the Department of Family Medicine at the University of Alberta, and lead author of the prospective cohort study. This time-series analysis used data from BC for new quinine prescriptions, as well as search data from Google Trends. The authors found that nocturnal leg cramps display striking seasonal variability, with incidence highest in summer and lowest in winter.

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